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ACROBiosystems Human B7-H3 / CD276 Protein, Fc Tag
MALS verified
374.99 € - 2419.31 €
Spezifikation
| Molekulargewicht | 49.9 kDa |
|---|---|
| Quelle | Human B7-H3, Fc Tag (B73-H5253) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Pro 245 (Accession # Q5ZPR3-2). |
| Immunogen | Leu 29 - Pro 245 |
| Lagerungsbedingungen | -20°C |
| Gen-Alias | B7-H3,CD276,B7 homolog 3 |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15805957
|
ACROBiosystems
B73-H5253-100UG |
100 μg |
374.99 €
100 Mikrogramm |
Verfügbar ab: 24-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
|
15815957
|
ACROBiosystems
B73-H5253-1MG |
1 mg |
2419.31 €
1 Milligramm |
Verfügbar ab: 24-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.9 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| 49.9 kDa | |
| Leu 29 - Pro 245 | |
| B7-H3,CD276,B7 homolog 3 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| Human B7-H3, Fc Tag (B73-H5253) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Pro 245 (Accession # Q5ZPR3-2). | |
| -20°C | |
| B7-H3 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |