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ACROBiosystems Human CD38 Protein, Mouse IgG2a Fc Tag, low endotoxin

low endotoxin

Marke:  ACROBiosystems CD8-H5253-50UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15896297

  • 399.17 € / 50 Mikrogramm
Verfügbar ab: 23-12-2022
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Beschreibung

Beschreibung

CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 56.9 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_001766.2
56.9 kDa
50 µg
Val 43 - Ile 300
CD38,T10,cADPr hydrolase 1
Unconjugated
50 mM Tris, 100 mM Glycine, pH7.5
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human CD38, mouse IgG2a Fc Tag, low endotoxin (CD8-H5253) is expressed from human 293 cells (HEK293). It contains AA Val 43 - Ile 300 (Accession # P28907-1).
-20°C
CD38
Mouse IgG Fc Tag
Less than 0.1 EU / µg by the LAL method.
Bio-Markers and CD Antigens
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Sicherheitsdatenblatt (SDS)
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