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ACROBiosystems Human NKp30 / NCR3 / CD337 Protein, Fc Tag

Marke:  ACROBiosystems NC3-H5259-100UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15887337

  • 319.33 € / 100 Mikrogramm
Verfügbar ab: 05-01-2023
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Beschreibung

Beschreibung

Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 39.5 kDa. The protein migrates as 50-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAH52582
39.5 kDa
100 µg
Leu 19 - Gly 135
NCR3,CD337,NKp30,1C7,LY117,MALS
Unconjugated
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human NKp30, Fc Tag (NC3-H5259) is expressed from human 293 cells (HEK293). It contains AA Leu 19 - Gly 135 (Accession # AAH52582).
-20°C
NKp30
Fc Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote