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STEMCELL Technologies Human Recombinant Activin A
Activin A
Marke: STEMCELL Technologies 78001.2
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
- Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins produced by many cell types throughout development (Gurdon et al.) It is a disulfide-linked homodimer (two beta-A chains) that binds to heteromeric complexes of a type I (Act RI-A and Act RI-B) and a type II (Act RII-A and Act RII-B) serine-threonine kinase receptor (Attisano et al.) Activins primarily signal through SMAD2/3 proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (McDowell et al.) Activin A maintains the undifferentiated state of human embryonic stem cells (James et al.; Xiao et al.) and also facilitates differentiation of human embryonic stem cells into definitive endoderm (D'Amour et al.)
Spezifikation
| Activin beta-A chain, EDF, Erythroid differentiation protein, FRP, FSH-releasing protein, INHBA, Inhibin beta-A chain, Inhibin beta-1 | |
| 1000 μg | |
| Endoderm, PSC-Derived; Mesoderm, PSC-Derived; Other; Pluripotent Stem Cells | |
| ≥95% |