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ACROBiosystems Human Serpin D1 / Heparin Cofactor II Protein, His Tag
Marke: ACROBiosystems HC2-H5224-1MG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Serpin D1 is also known as Heparin cofactor 2 (HCF2), Protease inhibitor leuserpin-2 (HLS2), Heparin cofactor II (HC-II), which belongs to the serpin family. HCF2 is expressed predominantly in liver. Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, SerpinD1 / HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). In a glycosaminoglycan-independent manner, serpinD1 / HC-II also inhibits chymotrypsin. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.7 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
AAH35028 | |
1 mg | |
Gly 20 - Ser 499 | |
SerpinD1,HCF2,HLS2,HC-II | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
55.7 kDa | |
Human Serpin D1, His Tag (HC2-H5224) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - Ser 499 (Accession # AAH35028). | |
-20°C | |
Serpin D1 | |
Human | |
50 mM Tris, 150 mM NaCl, pH 7.5 | |
HEK293 | |
Other Recombinant Proteins |