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ACROBiosystems Human TFPI-2 Protein, His Tag

Marke:  ACROBiosystems TF2-H5227-50UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15887737

  • 353.54 € / 50 Mikrogramm
Verfügbar ab: 05-01-2023
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Beschreibung

Beschreibung

Tissue Factor Pathway Inhibitor 2 (TFPI­2) is also known as placental protein 5 (PP5) and retinal pigment epithelial cell factor 1 (REF­1), is a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). TFPI2 is highly abundant in the full-term placenta and widely expressed in umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy. TFPI­2 may play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa and has no effect on thrombin. Reduced synthesis of TFPI-2 has been related to numerous pathophysiological processes such as inflammation, angiogenesis, atherosclerosis, retinal degeneration and tumor growth / metastasis.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.7 kDa. The protein migrates as 26-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_006519.1
22.7 kDa
50 µg
Asp 23 - Lys 213
TFPI2,PP5,REF1
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human TFPI-2, His Tag (TF2-H5227) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Lys 213 (Accession # NP_006519.1).
-20°C
TFPI-2
His Tag
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote