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ACROBiosystems Human TROP-2 / TACSTD2 Protein, His Tag
Marke: ACROBiosystems TR2-H5223-1MG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.8 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_002344.2 | |
1 mg | |
His 27 - Thr 274 | |
TACSTD2,GA733-1,M1S1,TROP2 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
29.8 kDa | |
Human TROP-2, His Tag (TR2-H5223) is expressed from human 293 cells (HEK293). It contains AA His 27 - Thr 274 (Accession # P09758-1). | |
-20°C | |
TROP-2 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Other Recombinant Proteins |