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Epredia™ Lab Vision™ Actin, Smooth Muscle, Ab-1 Mouse Monoclonal Antibody, 40μg/mL, BSA and azide
Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Epredia™ Caspase 8 (FLICE) Ab-3, Mouse Monoclonal Antibody.
Marke: Epredia™ MS-1143-P0
Weitere Details : Netto-Gewicht : 1.00000kg
Description
Caspase 8 binds to the death effector domain (DED) of FADD through an analogous DED domain present in tandem in the proform of the caspase 8 protein. Recruitment of caspase 8 to the Fas receptor results in oligomerization of the caspase 8 protein, which in turn drives its autoactivation through “self-cleavage”. Activated caspase 8 then activates other downstream caspases including caspase 9, thereby commiting the cell to undergo apoptosis.Host Species: Mouse
Clone: 8CSP03; same as 4.1.20
Isotype: IgG1
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: Recombinant full-length human Caspase 8 protein
Molecular Weight: 55 kDa
Positive Control: Jurkat cells
Cellular Localization: Cytoplasmic
Recommended for:
- Western Blotting
- Immunoprecipitation (Denatured verified)
Note:
USA: RUO; Int'l: RUO
Specifications
| Caspase 8 (FLICE) Ab-3 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 100 μL | |
| Apoptosis | |
| Human | |
| IgG1 |
| Immunoprecipitation, Western Blot | |
| 8CSP03; same as 4.1.20 | |
| Unconjugated | |
| Recombinant full length human Caspase 8 protein | |
| RUO | |
| Primary | |
| Concentrated |