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ACROBiosystems Mouse BCMA / TNFRSF17 Protein, Fc Tag
Marke: ACROBiosystems BCA-M5258-1MG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.1 kDa. The protein migrates as 36 kDa under reducing (R) condition (SDS-PAGE) due to O-linked glycosylation which has been verified by O-Glycosidase and NeurSpezifikation
NP_035738.1 | |
1 mg | |
Met 1 - Thr 49 | |
TNFRSF17,CD269,BCM,BCMA | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
32.1 kDa | |
Mouse BCMA, Fc Tag (BCA-M5258) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Thr 49 (Accession # O88472-1). | |
-20°C | |
BCMA | |
Mouse | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
Bio-Markers and CD Antigens |