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NRL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 17388-1-AP-150UL
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Nrl (neural retina leucine zipper) is a member of the Maf family of transcription factors, which characteristically contain a highly conserved basic leucine zipper (bZIP)-DNA binding motif. Both Nrl and c-Maf preferentially bind to T-MARE sites and are implicated in a wide variety of developmental and physiologic roles. The Maf-Nrl subfamily regulates the expression of cell type-specific genes in tissues of the hematopoietic system, cerebellum and developing hindbrain. Maf and Nrl proteins bind an extended AP-1-like sequence and can form heterodimers with Fos and Jun transcription factors. In retinal cells and photoreceptor cells, Nrl promotes the expression of rhodopsin through binding to the Nrl response element present in the rhodopsin promoter. Nrl is expressed throughout the developing central and peripheral nervous system during neuronal differentiation, and its expression is restricted to neocortex, brainstem and retinal neurons during adulthood.Spezifikation
NRL | |
Polyclonal | |
Unconjugated | |
NRL | |
D14S46E, neural retina leucine zipper, NRL, NRL MAF, RP27 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
18185, 290221, 4901 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.47 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P54845, P54846 | |
Nrl | |
NRL Fusion Protein Ag11277 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |